Early mammalian development following fertilisation is an idiosyncratic process that is thought to depend on cell position and orientation. Stem cell systems are exquisitely controlled through feedback mechanisms. Elucidating answers to either of these problems involves the application of population biology ideas and mathematical models.
Derek studied Biology at Yale University before arriving at Oxford on a 2014 Marshall Scholarship. He continues work from his time at Moffitt Cancer Center to investigate mathematical models of cancer disease and treatment. In this realm of mathematical oncology.
Derek’s DPhil project seeks to model hematopoietic and leukemic stem cells to create clinically relevant models for predicting disease, optimizing therapy, and suggesting novel routes of treating hematopoietic cancers.